Endothelial Function and Coronary Spastic Angina
نویسندگان
چکیده
منابع مشابه
Differential effects of calcium-channel blockers on vascular endothelial function in patients with coronary spastic angina.
BACKGROUND The effects of the 3 classes of L-type calcium-channel blockers (CCBs) on vascular endothelial function have not been clarified in patients with coronary vasospasm. METHODS AND RESULTS Twenty-five normotensive patients (age 64.0+/-1.4 years) with coronary vasospasm were randomly treated for 3 months with benidipine, diltiazem, and verapamil, which belong to the dihydropyridine, ben...
متن کاملTreatment of Coronary Spastic Angina, Particularly Medically Refractory Coronary Spasm
Coronary spasm plays an important role in the pathogenesis of variant angina as well as ischaemic heart diseases. Treatment with vasodilators such as long-acting calcium channel blockers and long-acting nitrates is generally effective in preventing coronary spasm; however, in some patients coronary spasm is refractory to standard therapy. Because of endothelial dysfunction, hyper-reactivity of ...
متن کاملCoronary Spastic Angina Induced after Oral Desmopressin (DDAVP) Administration
A 60-year-old man was prescribed oral desmopressin (1-deamino-8-D-arginine vasopressin acetate trihydrate; DDAVP) for nocturnal polyuria. One week after starting to take desmopressin, he frequently felt chest pain while resting. Coronary angiography revealed no organic stenosis; however, an acetylcholine provocation test showed severe coronary spasm with ST elevation. He was diagnosed with coro...
متن کاملNew protocol to detect coronary spastic angina without fixed stenosis.
A new combined test, accelerated exercise following mild hyperventilation (HV), was examined to determine whether it is effective at detecting a positive response in patients with pharmacologically-induced coronary vasospasm and near normal coronary arteries. Fifty-eight consecutive patients who underwent both triple non-invasive spasm provocation tests and diagnostic coronary angiography were ...
متن کاملLimited role of coronary angioplasty and stenting in coronary spastic angina with organic stenosis.
OBJECTIVES We investigated the efficacy of percutaneous coronary intervention (PCI) in patients with coronary spastic angina (CSA) and severe organic stenosis. BACKGROUND Coronary spasm occurs at the site of organic stenosis in most patients with CSA and severe stenosis, whereas multivessel spasm occurs frequently in those with normal coronary arteries. The incidence of multivessel spasm and ...
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ژورنال
عنوان ژورنال: Internal Medicine
سال: 2005
ISSN: 0918-2918,1349-7235
DOI: 10.2169/internalmedicine.44.91